CLAMOXAN 100 ML

Product Information

• COMPOSITION
• 1 ml of the preparation contains the following active substances:
• Amoxicillin (as Amoxicillin Trihydrate) – 140 mg;
• Clavulanic acid (as Potassium clavulanate) – 35 mg.
• Store in dark place, out of the reach of children at +5° to +25°С.
• Excipients.
• PHARMACOLOGICAL PROPERTIES
• Amoxicillin is a semi-synthetic antibiotic of penicillin group. It blocks the synthesis of bacterial cell walls, inhibits enzyme activity of transpeptidase and carboxypeptidase, and causes violations of osmotic balance that leads to death of pathogens at stage of development. Amoxicillin has wide bactericidal action and is active against Gram-positive and Gram-negative bacteria such as: Staphylococcus spp., Streptococcus, spp. (S.agalactiae, S.dysgalactiae, S.uberis), E.coli, Arcanobacteria (incl. A.pyogenes ), Corynebacteria spp., Clostridia spp, Bacillus anthracis, Actinomyces bovis, Bacillus cereus, Bacteroides (incl. strains, producing β-lactamase), Campilobacter spp., Klebsiella spp, Pasteurella spp., Escherichia coli, Salmonella spp., Proteus spp., Fusobacterium necrophorum, Haemophilus spp., Moraxella spp., Actinobacillus lignieres і i.
• Clavulanic acid is one of the natural metabolites of Streptomyces clavuligerus. It resembles penicillin in a structurally similar nucleus with a β-lactam ring. Clavulanic acid is an inhibitor of the β-lactamase enzyme, the action of which is initially active, and ultimately passes the inactivation. Clavulanic acid penetrates the bacterial cell wall and binds external and intracellular β-lactamase enzymes.
• Amoxicillin in combination with an inhibitor of this enzyme (clavulanic acid) broadens the spectrum of antimicrobial activity.
• After parenteral injection, the product is rapidly absorbed and distributed throughout the tissues of the body, reaching high concentrations in muscle tissues, liver, and kidneys.
• TARGET ANIMALS
• Cattle, pigs.
• INDICATIONS
• Treatment of cattle, pigs with diseases of the respiratory system (bronchitis, bronchopneumonia, rhinitis), urogenital system (metritis, endometritis, cystitis, urethritis, pyelonephritis), joints, skin and soft tissues (umbilical infections, wounds, abscesses, inflammations), as well as treatment of animals with leptospirosis, mastitis, agalactia in pigs, actinomycosis, erysipelas of pigs, parainfluenza and paratyphoid, caused by pathogens susceptible to Amoxicillin and Clavulanic acid.