ROSTRUM LARGE BREED 10 Tab

Rostrum^® Large Breed, is a broad spectrum antibacterial, recommended for the treatment of:

Gastrointestinal tract infections (E. coli, Salmonella spp., Proteus spp.).
Respiratory tract infections (Pasteurella spp., Bordetella spp., Klebsiella spp.).
Genital urinary infections such as nephritis, pyelonephritis, cystitis. (E. coli, Corynebacterium pyogenes, Staphylococcus aureus, Streptococcus spp.).
Skin infections.
Infections of the external auditory canal and otitis (E. coli, Staphylococcus aureus, Streptococcus spp.).
Dermatitis, infected wounds (E. coli, Klebsiella spp., Staphylococcus aureus, Streptococcus spp.).

Category: Drag Pharma

Product Description

SPECIES

Dogs.

DOSAGE FORM

Oral Tablets.

THERAPEUTIC ACTION

Antibacterial.

COMPOSITION

Each tablet contains:
Enrofloxacin ……………. 150 mg
Excipients q.s.p ……….. 1 tablet

INDICATIONS

Rostrum^® Large Breed, is a broad spectrum antibacterial, recommended for the treatment of:

Gastrointestinal tract infections (E. coli, Salmonella spp., Proteus spp.).
Respiratory tract infections (Pasteurella spp., Bordetella spp., Klebsiella spp.).
Genital urinary infections such as nephritis, pyelonephritis, cystitis. (E. coli, Corynebacterium pyogenes, Staphylococcus aureus, Streptococcus spp.).
Skin infections.
Infections of the external auditory canal and otitis (E. coli, Staphylococcus aureus, Streptococcus spp.).
Dermatitis, infected wounds (E. coli, Klebsiella spp., Staphylococcus aureus, Streptococcus spp.).

ROUTE OD ADMINISTRATION AND DOSAGE

Orally.

Dose of the active principle: 150 mg of Enrofloxacin / 30 Kg of weight per day for 7 to 10 days. Half the dose can be administered, twice a day.
Product dose: 1 tablet of 150 mg / 30 Kg of weight per day for 7 to 10 days.

DRUG INTERACTIONS

Compounds containing di or trivalent cations such as aluminum, calcium, magnesium, iron or zinc can decrease the absorption of Enrofloxacin. Thus, for example antacids containing cations (Mg2 +, Al3 +, Ca2 +) can bind to Enrofloxacin and prevent its absorption.
Sucralfate can inhibit the absorption of Enrofloxacin. It is recommended to separate both dosages for at least two hours.
Enrofloxacin administered with theophylline can increase your serum levels. In dogs, theophylline clearance was reduced by 43% when co-administered with Enrofloxacin at a dose of 5 mg / kg every 24 hours.
Concomitant administration with other drugs that have hepatic metabolism may affect the pharmacokinetics of one or both drugs.

CONTRAINDICATIONS

Enrofloxacin is contraindicated in animals with hypersensitivity to quinolones.
Do not administer to small to medium breed dogs, less than 1 year old, or to large breed dogs less than 1 ½ years old.
Do not administer to animals with cartilaginous growth disorders.
The use of Enrofloxacin can generate the formation of crystals in urine, for which it is recommended not to administer in dehydrated animals.
Its use in pregnancy and / or lactation is not recommended.

WARNINGS

Keep out of the reach of children.
Fluoroquinolones, such as Enrofloxacin, should not be used as the first line of treatment, unless there is no therapeutic alternative available. When used as a second treatment, it should be based on susceptibility studies.

ADVERSE EFFECTS

Arthropathies have been reported in immature animals, especially dogs. The risk of arthropathy increases when the dose is increased, however, it has also been reported when the recommended doses are used in dogs.
Other adverse effects that have been reported in very rare cases (less than 1 animal in 10,000 animals, including isolated reports) include vomiting, anorexia, increased liver enzymes, ataxia, seizures, depression, lethargy and nervousness.

OBSERVATIONS

Special precautions for disposal of unused product or waste material:
Discard any unused product remains in its original container. Dispose of this product waste carefully with household waste.